Electrocortical group neuron activity describe changes in neurotransmision cause by different factors. Such changes could by qualitative described by spectral analysis of electrocortical activity as a variation of relative spectral power in different frequency ranges. We used fractal dimension to compare treated animals with control to quantitativily describe degree of pathophysiological state. The aim of this study was to qualitativily and quantitatively evaluate effect of the stress and the neurodegeneration in animal model of chronic intoxication by aluminum. This animal model is comparible with Alzheimer’s disease and Parkinson disease. By spectral and fractal analysis we described changes in electrocortical activity of aluminum intoxication compare to physiological control. We used adult animals, during 6 weeks intraperitonealy treated with aluminum. Stress was cause by experimental treatmant and immobilization. Neurodegeneration was observed histologicaly. Results shows that decrease in delta range of spectral power and fractal dimension might be used for evaluation of pathophysiological state of stress and neurodegeneration.
| Published in | American Journal of BioScience (Volume 2, Issue 2) |
| DOI | 10.11648/j.ajbio.20140202.11 |
| Page(s) | 28-31 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2014. Published by Science Publishing Group |
Aluminium , Neurotoxicity, Neurodegeneration, Stress
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APA Style
Ljiljana Martać, Jelena Podgorac, Slobodan Sekulić, Ivan Čapo. (2014). Animal Model of Neurodegeneration and Stress Cause by Aluminum Toxicity. American Journal of BioScience, 2(2), 28-31. https://doi.org/10.11648/j.ajbio.20140202.11
ACS Style
Ljiljana Martać; Jelena Podgorac; Slobodan Sekulić; Ivan Čapo. Animal Model of Neurodegeneration and Stress Cause by Aluminum Toxicity. Am. J. BioScience 2014, 2(2), 28-31. doi: 10.11648/j.ajbio.20140202.11
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Download@article{10.11648/j.ajbio.20140202.11,
author = {Ljiljana Martać and Jelena Podgorac and Slobodan Sekulić and Ivan Čapo},
title = {Animal Model of Neurodegeneration and Stress Cause by Aluminum Toxicity},
journal = {American Journal of BioScience},
volume = {2},
number = {2},
pages = {28-31},
doi = {10.11648/j.ajbio.20140202.11},
url = {https://doi.org/10.11648/j.ajbio.20140202.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbio.20140202.11},
abstract = {Electrocortical group neuron activity describe changes in neurotransmision cause by different factors. Such changes could by qualitative described by spectral analysis of electrocortical activity as a variation of relative spectral power in different frequency ranges. We used fractal dimension to compare treated animals with control to quantitativily describe degree of pathophysiological state. The aim of this study was to qualitativily and quantitatively evaluate effect of the stress and the neurodegeneration in animal model of chronic intoxication by aluminum. This animal model is comparible with Alzheimer’s disease and Parkinson disease. By spectral and fractal analysis we described changes in electrocortical activity of aluminum intoxication compare to physiological control. We used adult animals, during 6 weeks intraperitonealy treated with aluminum. Stress was cause by experimental treatmant and immobilization. Neurodegeneration was observed histologicaly. Results shows that decrease in delta range of spectral power and fractal dimension might be used for evaluation of pathophysiological state of stress and neurodegeneration.},
year = {2014}
}
TY - JOUR T1 - Animal Model of Neurodegeneration and Stress Cause by Aluminum Toxicity AU - Ljiljana Martać AU - Jelena Podgorac AU - Slobodan Sekulić AU - Ivan Čapo Y1 - 2014/02/20 PY - 2014 N1 - https://doi.org/10.11648/j.ajbio.20140202.11 DO - 10.11648/j.ajbio.20140202.11 T2 - American Journal of BioScience JF - American Journal of BioScience JO - American Journal of BioScience SP - 28 EP - 31 PB - Science Publishing Group SN - 2330-0167 UR - https://doi.org/10.11648/j.ajbio.20140202.11 AB - Electrocortical group neuron activity describe changes in neurotransmision cause by different factors. Such changes could by qualitative described by spectral analysis of electrocortical activity as a variation of relative spectral power in different frequency ranges. We used fractal dimension to compare treated animals with control to quantitativily describe degree of pathophysiological state. The aim of this study was to qualitativily and quantitatively evaluate effect of the stress and the neurodegeneration in animal model of chronic intoxication by aluminum. This animal model is comparible with Alzheimer’s disease and Parkinson disease. By spectral and fractal analysis we described changes in electrocortical activity of aluminum intoxication compare to physiological control. We used adult animals, during 6 weeks intraperitonealy treated with aluminum. Stress was cause by experimental treatmant and immobilization. Neurodegeneration was observed histologicaly. Results shows that decrease in delta range of spectral power and fractal dimension might be used for evaluation of pathophysiological state of stress and neurodegeneration. VL - 2 IS - 2 ER -
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